This is caused by a lack of insulin, which opens the door for glucose to reach cells.
Insulin is either missing (as in type 1 diabetes, mostly found in young people) or cannot be produced in the required amounts (type 2 diabetes mellitus, mostly affecting adults who are overweight).
If the blood glucose cannot enter the body‘s cells, there will not enough energy for the metabolism.
This, in turn, leads to a lack of normal metabolism.
Type 1 diabetes develops mainly in young people who have a normal body weight.
The disease is a result of the deterioration of beta cells - part of the Langerhans cells in the pancreas.
After a period of very good control of blood glucose (known as the honeymoon phase, since a lot of insulin in released into the blood due to the deterioration of the beta-cells), the patient is likely to experience a period of critical illness, since this eventually results in a lack of insulin.
So the causes of diabetes are different: with type 2, it is caused by being overweight and in type 1 it‘s the result of a lack of insulin.
This is best achieved by an insulin-pump or intensive insulin therapy that mimicks the two parts of insulin secretion: the basal and the acute insulin secretion.
This means measuring the blood glucose level before eating and anticipating how much energy needs to be ingested in the following meal.
It leads to the units of insulin needed to maintain a normal blood glucose level 2 hours after the meal.
Type 1 diabetes can be cured only when an intact pancreatic organ is transplanted. A transplant would require immuno-suppressive therapy.
„ Diabetes can lead to blindness, apoplexy, heart attack or renal insufficiency, and in extreme cases to the need for dialysis.
This means that highly vascularised organs like the brain, the heart and the kidneys will be predominantly injured.
As a result, this can lead to blindness, apoplexy, myocardial infarction or renal insufficiency, and in extreme cases, to the need of dialysis.
This means consuming less calories and doing more physical exercise.